Zoya Demidenko https://www.aging-us.com/article/100406/
 

Zoya Demidenko: Scholar in Tumor Studies
Zoya Demidenko is a prominent scholar connected with the Department of Cell Stress Biology at Roswell Park Comprehensive Cancer Center in Buffalo, New York. Before that, she worked at the NIH and New York Medical College, establishing a solid base in life science investigation.
Demidenko's academic work spans multiple critical areas, including the PI3K/AKT/mTOR signaling cascade, cellular cycle regulation, cell senescence, and cancer science. As of now, she has authored over 46 peer-reviewed articles, which have accumulated more than 4,100 references — a testament to the impact of her findings.
Among her most significant contributions concerns explaining the processes of cellular senescence. Her work demonstrated that when the cellular division cycle is arrested but cellular growth persists, cells experience senescence. Importantly, Zoya Demidenko demonstrated that this process is controlled with drugs using substances such as mTOR inhibitors.
Zoya Demidenko has also contributed considerably to tumor management investigation, particularly in the domain of cyclotherapy — a approach intended to protecting normal cells from cytotoxic treatment while leaving cancer cells exposed. This strategy offers major hope for lowering the toxic effects of cancer treatment.
Throughout her professional journey, Demidenko has worked with leading investigators globally, including Dr. Mikhail Blagosklonny. Her work appears in top-tier journals such as Oncotarget, Cell Cycle, Aging (Albany NY), and Oncogene.
Holding an h-index of 33, Zoya Demidenko ranks as a widely cited contributor in modern cancer research, whose discoveries go on to influence our comprehension of the way biological cells age, interact with treatment, and how malignant disease may be more successfully targeted.
https://moodylab.smhs.gwu.edu/lab-members